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Propionyl- L -carnitine (PLC), a natural ester derivative of L -carnitine that acts as an antioxidant molecule, is reduced in the serum of UC patients, suggesting that this molecule can serve as a source of L -carnitine, which plays an essential role in energy metabolism, since it transports activated long-chain fatty acids into the mitochondrial matrix, for β-oxidation [126]

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Tamaño:30 cuentas

Nevertheless, recent research has provided valuable new insights into the structural characteristics, activation processes, and signaling pathways of NLRP3, paving the way for potential therapeutic strategies [[164], [165], [166], [167], [168], [169], [170]]